Article

TFAP2A+ embryonic progenitor cells undergo fate diversification to give rise to human amnion, germline, and mesoderm

2025-06-27

Abstract excerpt

Amnion, germline and mesoderm specification at the posterior end of the human embryo occur around the same time in vivo . Similarly, in vitro generation of germline and amnion is associated with mesoderm induction regardless of differentiation platform. Yet, the lineage relationships between amnion, germline and mesoderm remains unresolved. By adding Basement Membrane Extract (BME) to the media, we demonstrate e...

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Literature Corpus work: 19b23291-9974-534e-9415-bc743527edc0
DOI: 10.1101/2025.06.26.661839

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TFAP2A+ embryonic progenitor cells undergo fate diversification to give rise to human amnion, germline, and mesodermDOI 10.1101/2025.06.26.661839Read

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