Article

Cancer drivers and clonal dynamics in acute lymphoblastic leukaemia subtypes

2021-04-15

Abstract excerpt

<title>Abstract</title> <p>To obtain a comprehensive picture of composite genetic drivers events and clonal dynamics in subtypes of paediatric acute lymphoblastic leukaemia (ALL) we analysed tumour-normal whole genome sequencing and expression data from 361 newly diagnosed patients. We report the identification of both novel coding and structural drivers as well as recurrent non-coding variation in promoters and...

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Literature Corpus work: 798119ba-88ad-54e4-8e64-ebcdcbb0d601
DOI: 10.21203/rs.3.rs-366981/v1

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