Article
Genomics in acute lymphoblastic leukaemia: insights and treatment implications.
Nature reviews. Clinical oncology - 1 Jun 2015
Roberts Kathryn G, Mullighan Charles G
Abstract excerpt
Acute lymphoblastic leukaemia (ALL) is the commonest childhood cancer and an important cause of morbidity from haematological malignancies in adults. In the past several years, we have witnessed major advances in the understanding of the genetic basis of ALL. Genome-wide profiling studies, including microarray analysis and genome sequencing, have helped identify multiple key cellular pathways that are frequently...
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