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The genomic basis of childhood T-lineage acute lymphoblastic leukemia

2023-10-27

Abstract excerpt

<title>Abstract</title> <p>T-lineage acute lymphoblastic leukemia (T-ALL) is a high-risk tumor that has eluded comprehensive genomic characterization, in part due to the high frequency of non-coding genomic alterations resulting in oncogene deregulation. Here we report integrated genome and transcriptome sequencing of T-ALL tumor and remission samples obtained from over 1300 uniformly treated children with T-ALL,...

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Literature Corpus work
c352f455-086a-5ba1-b828-15edeb423c5f
DOI
10.21203/rs.3.rs-3488430/v1
Open publication

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