Article

Characterization of a potential antibiotic target site on the ribosome

2025-05-02

Abstract excerpt

The ribosome is a known antibiotic target, where various classes of small molecules impact different stages of translation. There are multiple modes of function, such as interfering with the decoding process, impeding movement of the nascent protein chain and occluding the catalytic center. In the present study, we used a range of computational methods to demonstrate a new mechanism by which small molecules may im...

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Literature Corpus work: 78ff95bd-be7a-57ee-bd41-0842e89761d2
DOI: 10.1101/2025.05.02.651724

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