Article

The killing of human gut commensal <i>E. coli</i> ED1a by tetracycline is associated with severe ribosome dysfunction

2023-07-06

Abstract excerpt

<h4>SUMMARY</h4> Ribosomes translate the genetic code into proteins. Recent technical advances have facilitated in situ structural analyses of ribosome functional states inside eukaryotic cells and the minimal bacterium Mycoplasma. However, such analyses of Gram-negative bacteria are lacking, despite their ribosomes being major antimicrobial drug targets. Here we compare two E. coli strains, a lab E. coli K-12...

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Literature Corpus work: 615bf66d-89d8-5b42-8f0c-e5ea682c067b
DOI: 10.1101/2023.07.06.546847

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