Article

Positive Selection Drives the Rapid Fixation of Dephosphorylation in IRF9

2022-04-18

Abstract excerpt

The arms race between humans and pathogens drives the evolution of the human genome. Here, based on the HPO (Human Phenotype Ontology) annotation, we focused on human genes related to recurrent infections of virus, (RVI), bacterial (RBI) and recurrent fungal infections (RFI) to understand positive selection on pathogen-responsive genes. Interestingly, cross-species positive selection analyses revealed that the pro...

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Literature Corpus work: 780bb13b-10d0-533c-b462-c2824825dabb
DOI: 10.21203/rs.3.rs-1556042/v1

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