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Article

Signatures of natural selection on mutations of residues with multiple posttranslational modifications.

Molecular biology and evolution - 1 Jul 2014

Gray Vanessa E, Liu Li, Nirankari Ronika, Hornbeck Peter V, Kumar Sudhir

Abstract excerpt

Posttranslational modifications (PTMs) regulate molecular structures and functions of proteins by covalently binding to amino acids. Hundreds of thousands of PTMs have been reported for the human proteome, with multiple PTMs known to affect tens of thousands of lysine (K) residues. Our molecular...

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Identifiers

PMID: 24739307
DOI: 10.1093/molbev/msu137
PMCID: PMC4069621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24739307-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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