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Article

Systematic detection of positive selection in the human-pathogen interactome and lasting effects on infectious disease susceptibility.

PloS one - 1 Jan 2018

Corona Erik, Wang Liuyang, Ko Dennis, Patel Chirag J

Abstract excerpt

Infectious disease has shaped the natural genetic diversity of humans throughout the world. A new approach to capture positive selection driven by pathogens would provide information regarding pathogen exposure in distinct human populations and the constantly evolving arms race between host and disease-causing agents. We created a human pathogen interaction database and used the integrated haplotype score (iHS)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29799843
DOI: 10.1371/journal.pone.0196676
PMCID: PMC5969750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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