Article
Genome-wide detection of selection and other evolutionary forces.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Xu Zhuofei, Zhou Rui
Abstract excerpt
As is well known, pathogenic microbes evolve rapidly to escape from the host immune system and antibiotics. Genetic variations among microbial populations occur frequently during the long-term pathogen-host evolutionary arms race, and individual mutation beneficial for the fitness can be fixed preferentially. Many recent comparative genomics studies have pointed out the importance of selective forces in the...
Topics
- Actinobacillus pleuropneumoniae
- Algorithms
- Animals
- Base Sequence
- Electronic Data Processing
- Evolution, Molecular
- Genome, Bacterial
- Homologous Recombination
- Molecular Sequence Data
- Mutation
- Open Reading Frames
