Article

Localized ribosome access and distal tuning via the <i>Listeria prfA</i> RNA thermometer

2026-04-09

Abstract excerpt

<h4>ABSTRACT</h4> RNA thermometers (RNATs) are temperature-responsive structures in 5′ untranslated regions (UTRs) of bacterial messenger RNA (mRNA) that control translation by modulating ribosome access. The Listeria monocytogenes prfA RNAT represses translation of PrfA (positive regulatory factor A), the master virulence regulator, at ambient temperature and activates it near the human host temperature (∼37 °C...

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Literature Corpus work: 77cb06a3-6fd5-574e-8149-9bebdf551d1f
DOI: 10.64898/2026.04.08.717274

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