Article

The gatekeeper of <i>Yersinia</i> type III secretion is under RNA thermometer control

2021-05-20

Abstract excerpt

Many bacterial pathogens use a type III secretion system (T3SS) as molecular syringe to inject effector proteins into the host cell. In the foodborne pathogen Yersinia pseudotuberculosis, delivery of the secreted effector protein cocktail through the T3SS depends on YopN, a molecular gatekeeper that controls access to the secretion channel from the bacterial cytoplasm. Here, we show that several checkpoints adjus...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bc049974-98fb-5ee9-b52c-ca4694168f1f
DOI: 10.1101/2021.05.20.444929

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The gatekeeper of <i>Yersinia</i> type III secretion is under RNA thermometer controlDOI 10.1101/2021.05.20.444929Read

Temperature-responsive in vitro RNA structurome of <i>Yersinia pseudotuberculosis</i>Semantic proximity Read

RNase-mediated reprogramming of <i>Yersinia</i> virulenceSemantic proximity Read

The oxidative stress response, in particular the <i>katY</i> gene, is temperature-regulated in <i>Yersinia pseudotuberculosis</i>Semantic proximity Read

A type IVB secretion system contributes to the pathogenicity of <i>Yersinia pseudotuberculosis</i> strains responsible for the Far East scarlet-like feverSemantic proximity Read

Expression hierarchy in the Yersinia type III secretion system established through YopD recognition of RNA.Semantic proximity Read

T6SS4 is heterogeneously expressed in <i>Y. pseudotuberculosis</i> and is a target for transcriptional and post-transcriptional regulationSemantic proximity Read

Hijacking of the pleiotropic cytokine interferon-γ by the type III secretion system of Yersinia pestis.Semantic proximity Read

Coiled-coils in the YopD translocator family: a predicted structure unique to the YopD N-terminus contributes to full virulence of Yersinia pseudotuberculosis.Semantic proximity Read

RpoN is required for a functional type III secretion system in <i>Yersinia pseudotuberculosis</i>Semantic proximity Read

Regulation of the Yersinia type III secretion system: traffic control.Semantic proximity Read

A multi-omic systems approach to elucidating <i>Yersinia</i> virulence mechanismsSemantic proximity Read

Translocation of YopJ family effector proteins through the VirB/VirD4 T4SS of <i>Bartonella</i>Semantic proximity Read