Article
SHAPE analysis of the htrA RNA thermometer from Salmonella enterica.
RNA (New York, N.Y.) - 1 Oct 2017
Choi Edric K, Ulanowicz Kelsey A, Nguyen Yen Anh H, Frandsen Jane K, Mitton-Fry Rachel M
Abstract excerpt
RNA thermometers regulate expression of some genes involved in virulence of pathogenic bacteria such as Yersinia, Neisseria, and Salmonella They often function through temperature-dependent conformational changes that alter accessibility of the ribosome-binding site. The 5'-untranslated region (UTR) of the htrA mRNA from Salmonella enterica contains a very short RNA thermometer. We have systematically...
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