Article

Obtaining Increased Functional Proteomics Insights from Thermal Proteome Profiling through Optimized Melt Shift Calculation and Statistical Analysis

2022-12-30

Abstract excerpt

<h4>ABSTRACT</h4> Thermal Proteome Profiling (TPP) is an invaluable tool for functional proteomics studies that has been shown to discover changes associated with protein-ligand, protein- protein, and protein-RNA interaction dynamics along with changes in protein stability resulting from cellular signaling. The increasing number of reports employing this assay has not been met concomitantly with advancements and...

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Literature Corpus work: 3cc70ae6-b1e6-56a0-b796-1bad2c27d78e
DOI: 10.1101/2022.12.30.522131

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