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Temperature-responsive in vitro RNA structurome of <i>Yersinia pseudotuberculosis</i>

13 Jun 2016

Abstract excerpt

RNA structures are fundamentally important for RNA function. Dynamic, condition-dependent structural changes are able to modulate gene expression as shown for riboswitches and RNA thermometers. By parallel analysis of RNA structures, we mapped the RNA structurome of Yersinia pseudotuberculosis at three different temperatures. This human pathogen is exquisitely responsive to host body temperature (37 °C), which...

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PMID: 27298343
DOI: 10.1073/pnas.1523004113

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