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Article

Utilizing a PTPN22 gene signature to predict response to targeted therapies in rheumatoid arthritis

2019-03-24

Abstract excerpt

Despite the development of several targeted therapies for rheumatoid arthritis (RA), there is still no reliable drug-specific predictor to assist rheumatologists in selecting the most effective targeted therapy for each patient. Recently, a gene signature caused by impaired induction of PTPN22 in anti-CD3 stimulated peripheral blood mononuclear cells (PBMC) was observed in healthy at-risk individuals. However, the...

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Literature Corpus work
77950bf7-f6df-5874-bde4-e0263d03f3b0
DOI
10.1101/586982
Open publication

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Utilizing a PTPN22 gene signature to predict response to targeted therapies in rheumatoid arthritisDOI 10.1101/586982
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