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Article

Genetic Polymorphism of PTPN22 in Autoimmune Diseases: A Comprehensive Review.

Medicina (Kaunas, Lithuania) - 2 Aug 2022

Tizaoui Kalthoum, Shin Jae Il, Jeong Gwang Hun, Yang Jae Won, Park Seoyeon, Kim Ji Hong, Hwang Soo Young, Park Se Jin, Koyanagi Ai, Smith Lee

Abstract excerpt

It is known that the etiology and clinical outcomes of autoimmune diseases are associated with a combination of genetic and environmental factors. In the case of the genetic factor, the SNPs of the PTPN22 gene have shown strong associations with several diseases. The recent exploding numbers of genetic studies have made it possible to find these associations rapidly, and a variety of autoimmune diseases were...

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Share to Autoimmune Diseases
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Immune System

Share to Lupus Erythematosus, Systemic

Share to Polymorphism, Single Nucleotide

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

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Identifiers

PMID: 36013501
DOI: 10.3390/medicina58081034
PMCID: PMC9415475

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