Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pathways to gene identification in rheumatoid arthritis: PTPN22 and beyond.

Immunological reviews - 1 Apr 2005

Gregersen Peter K

Abstract excerpt

Rheumatoid arthritis (RA), like other autoimmune diseases, has a complex genetic basis. Rapid technical advances in high-throughput genotyping and analysis have now reached a point where genes of low-to-moderate risk can be identified using a variety of study designs, including whole genome association studies. The availability of large, well-characterized populations of cases and controls are critical to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Autoimmunity
Share to Chromosomes, Human, Pair 18

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PTPN22 gene

Share to Polymorphism, Single Nucleotide

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to Protein Tyrosine Phosphatases

Source

Identifiers

PMID: 15790351
DOI: 10.1111/j.0105-2896.2005.00243.x

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pathways to gene identification in rheumatoid arthritis: PTPN22 and beyond.PMID 15790351Read ↗

Recent advances in the genetics of RA susceptibility.Semantic proximity Read ↗

PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritis.Semantic proximity Read ↗

PTPN22: the archetypal non-HLA autoimmunity gene.Semantic proximity Read ↗

Why is PTPN22 a good candidate susceptibility gene for autoimmune disease?Semantic proximity Read ↗

PTPN22: setting thresholds for autoimmunity.Semantic proximity Read ↗

The role of PTPN22 in the pathogenesis of autoimmune diseases: A comprehensive review.Semantic proximity Read ↗

Non-major histocompatibility complex rheumatoid arthritis susceptibility genes.Semantic proximity Read ↗

Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease.Semantic proximity Read ↗

PTPN22 gene polymorphism and susceptibility to rheumatoid arthritis (RA): Updated systematic review and meta-analysis.Semantic proximity Read ↗

Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans.Semantic proximity Read ↗

Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes.Semantic proximity Read ↗

Regulation of T Cell Signaling and Immune Responses by PTPN22.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.