Article

Systematic comparison of colocalization methods using protein quantitative trait loci

2025-11-07

Abstract excerpt

Colocalization is frequently performed as a step to triage findings from genetic investigations linking molecular and disease data. However, the reliability and consistency of the various colocalization methods is not well understood. In particular, it is unclear whether a non-colocalization result should be taken as a definitive sign that two traits do not share a genetic cause in the region of interest, or merel...

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Literature Corpus work: 765933a4-9b17-507b-bd99-b03d84f4634a
DOI: 10.1101/2025.11.07.686776

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