Article
Bayesian Genetic Colocalization Test of Two Traits Using coloc.
Current protocols - 1 Dec 2022
Rasooly Danielle, Peloso Gina M, Giambartolomei Claudia
Abstract excerpt
Genetic colocalization is an approach for determining whether a genetic variant at a particular locus is shared across multiple phenotypes. Genome-wide association studies (GWAS) have successfully mapped genetic variants associated with thousands of complex traits and diseases. However, a large proportion of GWAS signals fall in non-coding regions of the genome, making functional interpretation a challenge....
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