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Article

HLA allele-specific expression: Methods, disease associations, and relevance in hematopoietic stem cell transplantation.

Frontiers in immunology - 1 Jan 2022

Johansson Tiira, Partanen Jukka, Saavalainen Päivi

Abstract excerpt

Varying HLA allele-specific expression levels are associated with human diseases, such as graft versus host disease (GvHD) in hematopoietic stem cell transplantation (HSCT), cytotoxic T cell response and viral load in HIV infection, and the risk of Crohn's disease. Only recently, RNA-based next generation sequencing (NGS) methodologies with accompanying bioinformatics tools have emerged to quantify HLA...

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Identifiers

PMID: 36248878
DOI: 10.3389/fimmu.2022.1007425
PMCID: PMC9554311

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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