Article
Scavenger receptor class A member 5 (SCARA5) and suprabasin (SBSN) are hub genes of coexpression network modules associated with peripheral vein graft patency.
Journal of vascular surgery - 1 Jul 2016
Kenagy Richard D, Civelek Mete, Kikuchi Shinsuke, Chen Lihua, Grieff Anthony, Sobel Michael, Lusis Aldons J, Clowes Alexander W
Abstract excerpt
OBJECTIVE: Approximately 30% of autogenous vein grafts develop luminal narrowing and fail because of intimal hyperplasia or negative remodeling. We previously found that vein graft cells from patients who later develop stenosis proliferate more in vitro in response to growth factors than cells from patients who maintain patent grafts. To discover novel determinants of vein graft outcome, we have analyzed gene...
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