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Sequential Inflammatory and Matrisome Programs Drive Remodeling of the Mouse Carotid-Jugular Arteriovenous Fistula

2025-11-07

Abstract excerpt

The mouse carotid-jugular arteriovenous fistula (AVF) is a widely adopted surgical model to study venous remodeling after AVF creation. Despite its increasing use, the extent to which this model recapitulates the cellular and molecular remodeling processes observed in humans remains uncertain, which is essential for validating its translational relevance. Using bulk and single-cell RNA sequencing, we have depicted...

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Literature Corpus work
e01189f1-9ea8-52e0-a835-4014f9443dfd
DOI
10.20944/preprints202511.0461.v1
Open publication

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