Article

Integrated single-nuclei and spatial transcriptomic analysis reveals propagation of early acute vein harvest and distension injury signaling pathways following arterial implantation

2023-11-02

Abstract excerpt

<h4>Background</h4> Vein graft failure (VGF) following cardiovascular bypass surgery results in significant patient morbidity and cost to the healthcare system. Vein graft injury can occur during autogenous vein harvest and preparation, as well as after implantation into the arterial system, leading to the development of intimal hyperplasia, vein graft stenosis, and, ultimately, bypass graft failure. While previo...

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Literature Corpus work: 7a771234-0424-57a9-92d8-861d46c2a622
DOI: 10.1101/2023.10.31.564995

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