Article

Intrathecal mesenchymal stem cell therapy in progressive multiple sclerosis: cross-compartment immune profiling in the SMART-MS randomized trial

2026-05-12

Abstract excerpt

<title>Abstract</title> <p>Therapeutic options for progressive multiple sclerosis (MS) remain limited, and the biological mechanisms engaged by intrathecal mesenchymal stem cell (MSC) therapy are incompletely understood. MSCs are proposed to exert immunomodulatory and trophic effects, yet most studies rely on targeted biomarkers and lack systems-level analysis across immune compartments. Here, we applied an integ...

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Literature Corpus work: 75da16c6-89ff-530e-b370-05b190dddfec
DOI: 10.21203/rs.3.rs-9629755/v1

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