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Article

Targeted proteomics of cerebrospinal fluid in treatment naïve multiple sclerosis patients identifies immune biomarkers of clinical phenotypes.

Scientific reports - 18 Sept 2024

Rabin Alexandra, Bello Elisa, Kumar Saurabh, Zeki Dalia Abou, Afshari Khashayar, Deshpande Mugdha, Francis Nimmy, Khalighinejad Farnaz, Umeton Raffaella, Radu Irina, Qutab Fatima, Kwong Danny, Kurban Mariana, Hemond Christopher, Richmond Jillian M, Ionete Carolina

Abstract excerpt

Multiple sclerosis (MS) is an inflammatory demyelinating disease with heterogeneous clinical presentations and variable long-term disability accumulation. There are currently no standard criteria to accurately predict disease outcomes. In this study we investigated the cross-sectional relationship between disease phenotype and immune-modulating cytokines and chemokines in cerebrospinal fluid (CSF). We analyzed...

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Identifiers

PMID: 39294186
DOI: 10.1038/s41598-024-67769-1
PMCID: PMC11411093

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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