Article

Immune Cell Heterogeneity in Multiple Sclerosis Reveals Myeloid-Specific Dysfunction and Distinct Regulatory Programs Across CD14+, CD4+, and CD8+ Immune Cells

2026-07-07

Abstract excerpt

<title>Abstract</title> <p>Background Multiple Sclerosis (MS) is a neuroinflammatory and neurodegenerative disorder driven by dysregulated peripheral immune responses. Among immune cells, myeloid cells (CD14 + monocytes/macrophages) are key players in initiating and sustaining CNS inflammation, yet their cell‑specific molecular dysfunction remains incompletely understood. Methods We performed an integrated syst...

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Literature Corpus work: 2fcac961-25d0-5b1e-a729-d7ee25bb7859
DOI: 10.21203/rs.3.rs-9992392/v1

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