Article

Cholesterol catalyzes unfolding in membrane inserted motifs of the pore forming protein cytolysin A

2023-05-08

Abstract excerpt

Plasma membrane induced protein folding and conformational transitions play a central role in cellular homeostasis. Several transmembrane proteins are folded in the complex lipid milieu to acquire a specific structure and function. Bacterial pore forming toxins (PFTs) are proteins expressed by a large class of pathogenic bacteria that exploit the plasma membrane environment to efficiently undergo secondary structu...

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Literature Corpus work: 7573d8d2-71e1-5e7e-8a6e-c3ab8dd2af79
DOI: 10.1101/2023.05.07.539733

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