Article

Novel engraftment and T cell differentiation of human hematopoietic cells in <i>Art</i> <sup>-/-</sup> <i>IL2RG</i> <sup>-/</sup> SCID pigs

2019-05-02

Abstract excerpt

Pigs with severe combined immunodeficiency (SCID) are an emerging biomedical animal model. Swine are anatomically and physiologically more similar to humans than mice, making them an invaluable tool for preclinical regenerative medicine and cancer research. One essential step in further developing this model is the immunological humanization of SCID pigs. In this work we have generated T - B - NK - SCID pigs th...

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Literature Corpus work: 7543b181-0145-5762-854e-a42de64cd69e
DOI: 10.1101/614404

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