Article

Ptpn20 maintains choroid plexus epithelial integrity to preserve amyloid-β homeostasis in Alzheimer's disease

2026-08-25

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> The choroid plexus forms the blood–cerebrospinal fluid (CSF) barrier and plays a central role in brain homeostasis through CSF production and solute exchange. Although age-related choroid plexus dysfunction has been implicated in Alzheimer's disease (AD), the molecular mechanisms that preserve epithelial integrity and amyloid-β homeostasis remain poorly under...

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Literature Corpus work: 7520fb5f-17d1-5ebf-8cbc-d0246e373bf6
DOI: 10.21203/rs.3.rs-10596838/v1

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