Article

Ptpn20 regulates actin-dependent vesicular trafficking and amyloid-β clearance at the choroid plexus blood– CSF barrier

2026-03-26

Abstract excerpt

<title>Abstract</title> <p>Clearance of amyloid-β (Aβ) across brain barrier interfaces is increasingly recognized as a key determinant of its accumulation in Alzheimer’s disease. The choroid plexus (ChP), forming the blood–CSF barrier, contributes to cerebrospinal fluid turnover and solute exchange, yet the molecular mechanisms regulating epithelial vesicular trafficking remain incompletely understood. Here we sh...

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Literature Corpus work: 5c304db1-d57d-574d-be83-5266ba37ee0c
DOI: 10.21203/rs.3.rs-9182878/v1

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