Article

Ptpn20 preserves actin-dependent vesicular trafficking and amyloid-β clearance capacity in the choroid plexus

2026-02-16

Abstract excerpt

<title>Abstract</title> <p>Accumulation of amyloid-β (Aβ) in Alzheimer’s disease reflects not only excessive production but also impaired clearance. The choroid plexus (ChP), which forms the blood–cerebrospinal fluid barrier, plays an important role in cerebrospinal fluid turnover and molecular elimination; however, the mechanisms that maintain epithelial integrity and vesicle-mediated transport remain poorly und...

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Literature Corpus work: 557a89de-b4c0-585c-b48a-80b4e4761b31
DOI: 10.21203/rs.3.rs-8759264/v1

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