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Gene expression and functional annotation of human choroid plexus epithelium failure in Alzheimer’s disease

16 Nov 2015

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is the most common form of dementia. AD has a multifactorial disease etiology and is currently untreatable. Multiple genes and molecular mechanisms have been implicated in AD, including ß-amyloid deposition in the brain, neurofibrillary tangle accumulation of hyper-phosphorylated Tau, synaptic failure, oxidative stress and inflammation. Relatively little is known about the...

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PMID: 26573292
DOI: 10.1186/s12864-015-2159-z

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