Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative transcriptomics of choroid plexus in Alzheimer’s disease, frontotemporal dementia and Huntington’s disease: implications for CSF homeostasis

30 May 2018

Abstract excerpt

BACKGROUND: In Alzheimer's disease, there are striking changes in CSF composition that relate to altered choroid plexus (CP) function. Studying CP tissue gene expression at the blood-cerebrospinal fluid barrier could provide further insight into the epithelial and stromal responses to neurodegenerative disease states. METHODS: Transcriptome-wide Affymetrix microarrays were used to determine disease-related...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Cerebrospinal fluid and hydrocephalus
Share to Genetic Neurodegenerative Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29848382
DOI: 10.1186/s12987-018-0102-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative transcriptomics of choroid plexus in Alzheimer’s disease, frontotemporal dementia and Huntington’s disease: implications for CSF homeostasisPMID 29848382Read ↗

A Multi-omic Atlas of Human Choroid Plexus in Alzheimer’s DiseaseSemantic proximity Read ↗

Alterations in choroid plexus gene expression in Alzheimer’s disease provide inferences for CSF composition and dynamicsSemantic proximity Read ↗

Gene expression and functional annotation of human choroid plexus epithelium failure in Alzheimer’s diseaseSemantic proximity Read ↗

Early transcriptional and cellular abnormalities in choroid plexus of a mouse model of Alzheimer’s diseaseSemantic proximity Read ↗

Multi-modal choroid plexus pathology in aging and Alzheimer’s diseaseSemantic proximity Read ↗

Transcriptome profiling of cerebrospinal fluid in Alzheimer’s Disease reveals molecular dysregulations associated with diseaseSemantic proximity Read ↗

The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer’s diseaseSemantic proximity Read ↗

Cerebrospinal fluid proteomics in patients with Alzheimer’s disease reveals five molecular subtypes with distinct genetic risk profilesSemantic proximity Read ↗

Large-scale cerebrospinal fluid proteomic analysis in Alzheimer’s disease patients reveals five molecular subtypes with distinct genetic risk profilesSemantic proximity Read ↗

Mechanobiological Specialization of Choroid Plexus Macrophages Defined by Titin ExpressionSemantic proximity Read ↗

Choroid plexus enlargement in acute neuroinflammation is tightly interrelated to the tyrosine receptor signallingSemantic proximity Read ↗

Signatures for Viral Infection and Inflammation in the Proximal Olfactory System in Familial Alzheimer’s DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.