Article

m <sup>6</sup> A depletion attenuates the macrophage type I interferon response

2026-08-17

Abstract excerpt

Macrophages play an important role in coordinating the antiviral response and post-transcriptional regulation of mRNA is an important element of the inflammatory gene expression required for defense against viral pathogens. N6-methyladenosine (m 6 A) deposition on mRNA by METTL3 constitutes one such post-transcriptional event which facilitates a cascade of downstream regulation via RNA decay and translation. We d...

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Literature Corpus work: 740e9caf-c84a-5ac7-90ef-ffd48c360659
DOI: 10.64898/2026.08.14.744930

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