Article

Comprehensive characterisation of molecular host-pathogen interactions in influenza A virus-infected human macrophages

2019-06-17

Abstract excerpt

Macrophages in the lung detect and respond to influenza A virus (IAV), determining the nature of the immune response. Using terminal depth 5’-RNA sequencing (CAGE) we quantify transcriptional activity of both host and pathogen over a 24-hour timecourse of IAV infection in primary human monocyte-derived macrophages (MDM). We use a systems approach to describe the transcriptional landscape of the host response to IA...

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Literature Corpus work: d9c5a8e4-bb78-5b78-a0a9-dd2daa280866
DOI: 10.1101/670919

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