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Matrine improves bile acid metabolism and reduces inflammatory and oxidative stress in inflammatory bowel disease (IBD) via suppressing JAK2 pathway

2025-10-19

Abstract excerpt

<title>Abstract</title> <p> Background Inflammatory bowel disease (IBD) is a chronic inflammatory disorder often involving bile acid malabsorption. While the natural compound matrine has known anti-inflammatory properties, its therapeutic mechanism in IBD is unclear. This study aimed to elucidate matrine's potential by identifying its molecular targets and effects in IBD. Methods First, bioinformatics and molecu...

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Literature Corpus work
740d8f0d-d4eb-5194-ac7c-b93788184132
DOI
10.21203/rs.3.rs-7421995/v1
Open publication

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Matrine improves bile acid metabolism and reduces inflammatory and oxidative stress in inflammatory bowel disease (IBD) via suppressing JAK2 pathwayDOI 10.21203/rs.3.rs-7421995/v1
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