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Bile acid metabolism in health and ageing-related diseases

22 May 2024

Abstract excerpt

Bile acids (BAs) have surpassed their traditional roles as lipid solubilizers and regulators of BA homeostasis to emerge as important signalling molecules. Recent research has revealed a connection between microbial dysbiosis and metabolism disruption of BAs, which in turn impacts ageing-related diseases. The human BAs pool is primarily composed of primary BAs and their conjugates, with a smaller proportion...

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PMID: 38788963
DOI: 10.1016/j.bcp.2024.116313

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