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The Conversion of Evodiamine-induced Hepatotoxicity into a Therapeutic Effect on Colonitis: Insight from the Liver-Gut Axis Mediated by PPAR/NF-κB/ZO-1/caspase-3 Pathway

2025-09-19

Abstract excerpt

<title>Abstract</title> <p>Background Evodiamine (EVO) exerts promising therapeutic potential in treating Ulcerative Colitis (UC). However, application in clinical practice is constrained by concerns regarding potential hepatotoxicity. Understanding the mechanisms behind EVO's hepatotoxic effects and its therapeutic benefits is therefore essential to enhance its safe and effective application in clinical practice...

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Literature Corpus work
e01ed833-8e57-5761-aa6b-f9464efbc090
DOI
10.21203/rs.3.rs-7515324/v1
Open publication

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The Conversion of Evodiamine-induced Hepatotoxicity into a Therapeutic Effect on Colonitis: Insight from the Liver-Gut Axis Mediated by PPAR/NF-κB/ZO-1/caspase-3 PathwayDOI 10.21203/rs.3.rs-7515324/v1
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