Article

Pan-repository analysis reveals a drug-activating function of microbial bile acid conjugation

2026-03-04

Abstract excerpt

Microbially modified bile acids shape host physiology by regulating nutrient absorption, glucose homeostasis, circadian rhythms and thermoregulation. Here we identify a previously unrecognized drug-activating function of microbial bile acid conjugation. By systematically mining human LC–MS/MS datasets across public repositories and linking uncharacterized bile acid spectra to health-associated metadata, we discove...

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Identifiers and source

Literature Corpus work: 17b9c127-a6f5-5bb9-87d7-58aeab9b2d80
DOI: 10.64898/2026.03.03.709330

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