Article

Definition of a Small Core Transcriptional Circuit Regulated by AML1-ETO

2020-06-15

Abstract excerpt

Transcription factors regulate gene networks controlling normal hematopoiesis and are frequently deregulated in acute myeloid leukemia (AML). Critical to our understanding of the mechanism of cellular transformation by oncogenic transcription factors is the ability to define their direct gene targets. While this seems to be a straight forward task, gene network cascades can change within minutes to hours, making i...

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Literature Corpus work: 73f36d96-87c6-5add-a7b6-30e00c1ce76e
DOI: 10.1101/2020.06.14.151159

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