Article

Utilizing combined spatial transcriptomics to elucidate localized immune responses within human coronary arteries throughout the progression of atherosclerosis

2025-03-01

Abstract excerpt

Atherosclerosis is a complex inflammatory disease characterized by the accumulation of lipids and immune cells in the arterial wall, leading to the narrowing and stiffening of blood vessels. The involvement of both innate and adaptive immunity in the pathogenesis of human atherosclerosis is increasingly recognised. However, the spatial organization and specific roles of immune cells during the various stages of di...

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Literature Corpus work: 11509d46-9aa4-591d-9585-bb7fc47877c6
DOI: 10.1101/2025.02.20.639291

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