Article
Heterogeneity of immune cells in human atherosclerosis revealed by scRNA-Seq.
Cardiovascular research - 22 Nov 2021
Vallejo Jenifer, Cochain Clément, Zernecke Alma, Ley Klaus
Abstract excerpt
Immune cells in atherosclerosis include T, B, natural killer (NK) and NKT cells, macrophages, monocytes, dendritic cells (DCs), neutrophils, and mast cells. Advances in single-cell RNA sequencing (sRNA-Seq) have refined our understanding of immune cell subsets. Four recent studies have used scRNA-Seq of immune cells in human atherosclerotic lesions and peripheral blood mononuclear cells (PBMCs), some including...
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