Article
New Classification of Macrophages in Plaques: a Revolution.
Current atherosclerosis reports - 18 Jun 2020
Deng Hao, Sun Yingxin, Zeng Wenyun, Li Huhu, Guo Maojuan, Yang Lin, Lu Bin, Yu Bin, Fan Guanwei, Gao Qing, Jiang Xijuan
Abstract excerpt
PURPOSE: Macrophages play vital roles in the development of atherosclerosis in responding to lipid accumulation and inflammation. Macrophages were classified as inflammatory (M1) and alternatively activated (M2) macrophage types based on results of in vitro experiments. On the other hand, the composition of macrophages in vivo is more complex and remains unresolved. This review summarizes the transcriptional...
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