Article
The druggable genome and support for target identification and validation in drug development
2016-07-26
Abstract excerpt
Target identification (identifying the correct drug targets for each disease) and target validation (demonstrating the effect of target perturbation on disease biomarkers and disease end-points) are essential steps in drug development. We showed previously that biomarker and disease endpoint associations of single nucleotide polymorphisms (SNPs) in a gene encoding a drug target accurately depict the effect of modi...
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Identifiers and source
- Literature Corpus work
- 73a51278-9184-5c39-9f2e-2ce9a291a8ce
- DOI
- 10.1101/066027