Article
Advancing the use of genome-wide association studies for drug repurposing.
Nature reviews. Genetics - 1 Oct 2021
Reay William R, Cairns Murray J
Abstract excerpt
Genome-wide association studies (GWAS) have revealed important biological insights into complex diseases, which are broadly expected to lead to the identification of new drug targets and opportunities for treatment. Drug development, however, remains hampered by the time taken and costs expended to achieve regulatory approval, leading many clinicians and researchers to consider alternative paths to more immediate...
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