Article
Systems biology approach for new target and biomarker identification.
Current topics in microbiology and immunology - 1 Jan 2013
Wang I-Ming, Stone David J, Nickle David, Loboda Andrey, Puig Oscar, Roberts Christopher
Abstract excerpt
The pharmaceutical industry is spending increasingly large amounts of money on the discovery and development of novel medicines, but this investment is not adequately paying off in an increased rate of newly approved drugs by the FDA. The post-genomic era has provided a wealth of novel approaches for generating large, high-dimensional genetic and transcriptomic data sets from large cohorts of preclinical species...
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