Article

The sequence and structure of the Mfd protein dictate its role during virulence

2026-08-25

Abstract excerpt

<title>Abstract</title> <p> The Mfd (Mutation Frequency Decline) protein is a ubiquitous RNA-polymerase (RNAP)-associated factor, responsible for displacing RNAP, stalled onto DNA lesions, and for recruiting UvrA of the NER (Nucleic Excision Repair) complex, ensuing a boosting in DNA repair. Recent studies in <italic>E. coli</italic> and <italic>B. subtilis</italic> showed that Mfd regulates transcription dy...

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Literature Corpus work: 72ab6b69-fde2-53fb-8b34-f06688e2edc2
DOI: 10.21203/rs.3.rs-10606469/v1

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