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Article

Cellular and molecular phenotypes depending upon the RNA repair system RtcAB of Escherichia coli.

Nucleic acids research - 16 Nov 2016

Engl Christoph, Schaefer Jorrit, Kotta-Loizou Ioly, Buck Martin

Abstract excerpt

RNA ligases function pervasively across the three kingdoms of life for RNA repair, splicing and can be stress induced. The RtcB protein (also HSPC117, C22orf28, FAAP and D10Wsu52e) is one such conserved ligase, involved in tRNA and mRNA splicing. However, its physiological role is poorly described, especially in bacteria. We now show in Escherichia coli bacteria that the RtcR activated rtcAB genes function for...

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PMID: 27402162
DOI: 10.1093/nar/gkw628
PMCID: PMC5175333

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