Article

Clinico-genomic features predict distinct metastatic phenotypes in cutaneous melanoma

2025-01-27

Abstract excerpt

Metastasis drives mortality and morbidity in cancer. While some patients develop broad metastatic disease across multiple organs, others exhibit organ-specific spread. To identify mechanisms underlying metastatic organotropism, we analyzed clinico-genomic data from over 7,000 patients with metastatic cutaneous melanoma in three independent cohorts (one primary discovery and two validation cohorts including a natio...

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Literature Corpus work: 727d3c70-20c5-5339-8c26-6314f2f665fa
DOI: 10.1101/2025.01.24.633441

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